Yes, you can use the minimax algorithm here.
The problem statement says that the winner of the game is "the girl who has more candies at the end of the game." So one reasonable scoring function you could use is the difference in the number of candies held by the first and second player.
Does this mean that the second player also plays optimally to win the game?
Yes. When you are evaluating a MIN level, the MIN player will always choose the path with the lowest score for the MAX player.
Note: both the MIN and MAX levels can be implemented with the same code, if you evaluate every node from the perspective of the player making the move in that round, and convert scores between levels. If the score is a difference in number of candies, you could simply negate it between levels.
Trying to choose some path in order to minimize the first player's chances of winning also means trying to win?
Yes. The second player is trying to minimize the first player's score. A reasonable scoring function will give the first player a lower score for a loss than a tie.
I wonder whether we can apply the minimax algorithm here.
Yes. If I've read the problem correctly, the number of levels will be equal to the number of boxes. If there's no limit on the number of boxes, you'll need to use an n-move lookahead, evaluating nodes in the minimax tree to a maximum depth.