With the modern IDEs such as VS 2012, is there a significant performance difference in going with code created by visual tools (such as Visual Studio, Qt, etc.) rather than writing the code from scratch? I remember when I first tried Dreamweaver back in 2003, I couldn't stand the fact that it bloated the code with nonsense. From there on I've had a distrust with visual-style creation of applications. Now that I'm picking up pace in computer programming, I would like to optimize the way I do things. Due to the fact that I don't have enough experience, I can't answer my own question.
I am not looking for preference in one over the other, so this is not a discussion of which one is better. I am more interested in answers from those who have noticed the difference in performance between the two ways of creating applications.
EDIT (08/18/2013): Besides the wonderful answers that people gave me, I thought I'd add this for anyone who's researching into performance. I've been reading Beginning Visual C# 2012 Programming and in there I found something very important and impressive:
As with partial classes, partial methods are useful when it comes to customizing auto-generated or designer-created code. The designer may declare partial methods that you can choose to implement or not depending on the situation. If you don’t implement them, you incur no performance hit because effectively the method does not exist in the compiled code.
So, all that extra "junk" that is being created won't effect the performance if no implementation occurred. Things have come a long way and I couldn't be happier in that regard.