I have a working cross compile of Python, however I've tried cross compiling the py-smbus extension from i2c-tools using distutilscross and can't get past the command line.
The documentation (https://pypi.python.org/pypi/distutilscross) suggests that it should be as easy as python setup.py build -x
(after setting appropriate environment variables), however when I run that command the '-x' triggers a bad-argument error.
Does anyone know how to fix this?