You should send a message to the isolate, telling it to stop. You can simply do something like:
port.send('STOP');
To be clear, isolates and futures are two different things, and you use them differently.
Use an isolate when you want some code to truly run concurrently, in a separate "isolated memory heap". An isolate is like a mini program, running separately from your main program. You send isolates messages, and you can receive messages from isolates.
Use a future when you want to be notified when a value is available later. "Later" is defined as "a future tick in the event loop". Each isolate has its own event loop. It's important to understand that just asking a Future to run a function doesn't make the function run in parallel. It just puts the function onto the event loop to be run "later".