RPC == "Remote Procedure Call"
Essentially, its the idea that communications between two endpoints is best modeled on the concept of those endpoints making logical function calls on each other. In general one side "publishes" an API in some way (for example, if your using SOAP, typically you'll have a file called a WSDL (pronounced wizdel) that enumerates the functions you respond to... a client will first download your WSDL and then make calls to your available API's)... These days, almost all of the available technologies will layer their specific protocols on top of HTTP (for example Web Services, UPnP, REST).. This generally means you're servers are implemented on top of web servers...
So, if all you need to implement is the client side, then you can probably use libcurl for all of your HTTP needs...