Yes, it is possibile. It can be done by using the disabled
property of the option tag:
<select id="payments" name="payments" style="width:250px;">
<option value="" data-description="Choos your payment gateway">Payment Gateway</option>
<option value="amex" data-image="http://www.marghoobsuleman.com/mywork/jcomponents/image-dropdown/samples/images/msdropdown/icons/Amex-56.png" data-description="My life. My card...">Amex</option>
<option value="Discover" data-image="http://www.marghoobsuleman.com/mywork/jcomponents/image-dropdown/samples/images/msdropdown/icons/Discover-56.png" data-description="It pays to Discover...">Discover</option>
<option value="Mastercard" data-image="http://www.marghoobsuleman.com/mywork/jcomponents/image-dropdown/samples/images/msdropdown/icons/Mastercard-56.png" data-title="For everything else..." data-description="For everything else...">Mastercard</option>
<option value="cash" data-image="http://www.marghoobsuleman.com/mywork/jcomponents/image-dropdown/samples/images/msdropdown/icons/Cash-56.png" data-description="Sorry not available..." disabled="true">Cash on devlivery</option>
<option value="Visa" data-image="http://www.marghoobsuleman.com/mywork/jcomponents/image-dropdown/samples/images/msdropdown/icons/Visa-56.png" data-description="All you need...">Visa</option>
<option value="Paypal" data-image="http://www.marghoobsuleman.com/mywork/jcomponents/image-dropdown/samples/images/msdropdown/icons/Paypal-56.png" data-description="Pay and get paid...">Paypal</option>
</select>
The option 'cash' will be disabled.
Here is a working fiddle: http://jsfiddle.net/NKQRj/1/
EDIT
In this second example data are loaded from JSON data using:
$("#payments").msDropDown({byJson:{data:jsonData, name:'payments2'}}).data("dd");
to fill the elements.
You can define your options as disabled in your JSON data using disabled: true
property:
{image:'http://www.marghoobsuleman.com/mywork/jcomponents/image-dropdown/samples/images/msdropdown/icons/Cash-56.png', description:'Sorry not available...', value:'cash', text:'Cash on devlivery', disabled:true},
here is a working fiddle: http://jsfiddle.net/NKQRj/3/