You're right. Reading data in larger batches is usually a key part of speeding up file reads. Another part is pre-allocating the destination variable zeros, for example, a zeros
call.
I would do something like this:
%Pre-allocate
x0 = zeros(Ntot,1);
y0 = zeros(Ntot,1);
z0 = zeros(Ntot,1);
%Define a desired batch size. make this as large as you can, given available memory.
batchSize = 10000;
%Use while to step through file
indexCurrent = 1; %indexCurrent is the next element which will be read
while indexCurrent <= Ntot
%At the end of the file, we may need to read less than batchSize
currentBatch = min(batchSize, Ntot-indexCurrent+1);
%Load a batch of data
tmpLoaded = fread(fid, currentBatch*3, 'read*8')';
%Deal the fread data into the desired three variables
x0(indexCurrent + (0:(currentBatch-1))) = tmpLoaded(1:3:end);
y0(indexCurrent + (0:(currentBatch-1))) = tmpLoaded(2:3:end);
z0(indexCurrent + (0:(currentBatch-1))) = tmpLoaded(3:3:end);
%Update index variable
indexCurrent = indexCurrent + batchSize;
end
Of course, make sure you test, as I have not. I'm always suspicious of off-by-one errors in this sort of work.