If it's a TCP packet, then it'll be accurate as to the sending host. IPs in TCP packets cannot be spoofed unless you've got control of the routers involved. With spoofed source packets, only the initial SYN packet will come back, and then the SYN+ACK response from the server will go to the spoofed address, not wherever the forgery came from - e.g. you cannot do the full 3-way handshake unless you can control packet routing from the targetted machine.
UDP packets, on the other hand, can be trivially forged and you cannot trust anything about them.
As well, even simple things like proxy servers and NAT gateways can cloak the 'real' ip from where the packet originated. You'll get an IP, but it'll be the IP of the gateway/proxy, not the original machine.