Considering that this question is asked some years ago, I will try to add more to it based on the current technologies.
As of ECMAScript 6, metaprogramming is now supported in a sense via Symbol, Reflect and Proxy objects.
By searching on the web, I found a series of very interesting articles on the subject, written by Keith Kirkel:
Metaprogramming in ES6: Symbols and why they're awesome
In short, Symbols are new primitives that can be added inside an object (without practically being properties) and are very handy for passing metaprogramming properties to it among others. Symbols are all about changing the behavior of existing classes by modifying them (Reflection within implementation).
Metaprogramming in ES6: Part 2 - Reflect
In short, Reflect is effectively a collection of all of those “internal methods” that were available exclusively through the JavaScript engine internals, now exposed in one single, handy object. Its usage is analogous to the Reflection capabilities of Java and C#. They are used to discover very low level information about your code (Reflection through introspection).
Metaprogramming in ES6: Part 3 - Proxies
In short, Proxies are handler objects, responsible for wrapping objects and intercepting their behaviors through traps (Reflection through intercession).
Of course, these objects provide specific metaprogramming capabilities, much more restrictive compared to metaprogramming languages, but still can provide handy ways of basic metaprogramming, mainly through Reflection practices, in fact.
In the end, it is worth mentioning that there is some worth-noticing ongoing research work on staged metaprogramming in JavaScript.