I have recently started working with Wordpress MS (the new WPMU). I have just installed everything and have a few different domains working off of the same Wordpress MS install.
I am using the WordPress MU Domain Mapping plugin to handle different domain names.
Problem I am having is working with permalinks. I would like the URL to display something like this http://blakebullis.me/sample-post/ ... but whenever I change the permalink settings to be more SEO friendly I get a 404 error. The page only works properly when I use the default permalink settings http://blakebullis.me/?page_id=2