Goaded by @Mitch Wheat's unarguable assertion that my original post here was not an answer, here's an attempt to recast it as an answer:
I work mostly on HPC in the energy sector. Some of the computations that my scientist colleagues run take O(10^5) CPU-hours, we're seriously thinking about O(10^6) CPU-hours jobs in the near future.
I get well paid to squeeze every last drop of performance out of our codes, I'd think it was a good day's work if I could knock 1% off the run-time of some of our programs. Sometimes it has taken me a month to get that sort of performance improvement, sure I may be slow, but it's still cost-effective for our scientists.
I shudder therefore, when bright salespeople offering the latest and best in data center software (of which virtualization is one aspect) which will only, as I see it, shackle my codes to a pile of anchor chain from a 250,00dwt tanker (that was a metaphor).
I have read the question carefully and understand that OP is not proposing that virtualization would help, I'm offering the perspective of a practitioner. If this is still too much of a comment, do the SO thing and vote to close, I promise I won't be offended !