According to the Los Angeles Times, September 14 1996:
[Tupac Shakur] was pronounced dead at 4:03 p.m. at University Medical
Center of respiratory failure and cardiopulmonary arrest, a hospital
spokesman said.
(...)
Shakur was taken to University Medical Center, where surgeons removed
his right lung. He remained on a respirator in intensive care until
his death.
Of course, those who believe that Tupac faked his own death (or something like that) are unlikely to be convinced by this. (I mean, assuming that Tupac had the resources to pull that off, he should have at least thought of including the hospital in the conspiracy.)
However, OP doesn't mention any such details like the hospital lying, etc., so I see no need to evaluate that.
Various theories feature different pieces of alleged evidence that Tupac is alive. Since none of them are mentioned in OP, I've got nothing specific to assess. The list would be too long.
OP links to a newspaper article. That article discusses many claims. I'm not going to discuss those in detail either since OP doesn't present those claims. Therefore, it's outside of the scope of this answer. However, I'll note that the article itself does address those claims and presents arguments suggesting that they are false.