I have application servers with memcached running on them.
What will happen if I make a request to memcached on 10.243.98.5, which just happens to be the originating server? Will it use the same fast-path tcp/ip stack as 127.0.0.1, or would I get better performance by checking if 10.243.98.5 is the same box, and substituting 127.0.0.1?
Normally it wouldn't matter so much, because odds are the item you want is going to be in a memcached on another application server, but in this case the load-balancer divides requests so that it's very likely that most of the memcached requests will resolve to the local memcached instance.