I had a problem with CPU7 overload. I found that it was caused by the eth0 interrupts, as you can see on below cat /proc/interrupts. I'm using 2.6.35.2 kernel and Quad-Core AMD Opteron(tm) Processor 2354. I would like that interrupt were supported by all cores so I've tried to echo ff > /proc/irq/16/smp_affinity but it's not working. If I set 1, 2, 4, 8, 16 etc. it works for each core but not for several. I also have other servers where smp_affinity is set to "ff" and it works, but these machines runs on intel.
CPU0 CPU1 CPU2 CPU3 CPU4 CPU5 CPU6 CPU7
0: 126 0 0 0 0 0 0 0 IO-APIC-edge timer
1: 0 0 0 0 0 0 0 8 IO-APIC-edge i8042
9: 0 0 0 0 0 0 0 0 IO-APIC-fasteoi acpi
10: 0 0 0 0 0 0 0 2 IO-APIC-fasteoi ehci_hcd:usb1, ohci_hcd:usb2, ohci_hcd:usb3
11: 0 0 0 0 0 0 0 0 IO-APIC-fasteoi sata_svw
14: 0 0 0 0 0 0 0 44 IO-APIC-edge ide0
16: 523739 38196 20957 1288960 40051 33985 99858 12142246 IO-APIC-fasteoi eth0
28: 33784 0 1 24 0 4 1017 199001 IO-APIC-fasteoi megasas
NMI: 0 0 0 0 0 0 0 0 Non-maskable interrupts
LOC: 51149605 52755152 47000502 38164758 47335488 49653390 44361349 19201949 Local timer interrupts
SPU: 0 0 0 0 0 0 0 0 Spurious interrupts
PMI: 0 0 0 0 0 0 0 0 Performance monitoring interrupts
PND: 0 0 0 0 0 0 0 0 Performance pending work
RES: 29252262 26917272 17461908 9927632 26959155 24081482 15451952 5680615 Rescheduling interrupts
CAL: 86814 186 188 177 9656 176 169 176 Function call interrupts
TLB: 13134 52049 17599 15275 9937 18316 15062 9433 TLB shootdowns
ERR: 0
MIS: 0
Best regards, Andrew