The following is appearing in the application server role events.
The machine-default permission settings do not grant Local Activation permission for the COM Server application with CLSID {000C101C-0000-0000-C000-000000000046} to the user [Domain][User] SID ([SID]) from address LocalHost (Using LRPC). This security permission can be modified using the Component Services administrative tool.
I've solved a similar (application permission) problem on "IIS WAMREG admin Service" before by going into Component Services and assigning the correct permissions (Activate & Launch). However, the previous method seems impossible as all the properties are disabled for app id {000C101C-0000-0000-C000-000000000046}, also I noticed that it doesn't have a name - there are a few applications without a name, but the properties aren't disabled on them.
This is a fresh install of server 2008 (Std not R2) with sharepoint server 2010. Nothing appears to be "broken" that I notice, but I get many errors (over 100 for a single minute around 1am) in the event log and this isn't fun.
I've found a few pointers on google here, here & here, but am not convinced I should be changing the registry to solve this. According to this the app is MSIServer, but that doesn't appear. Does anyone know what the problem is, and why this is happening, and why I can't change the properties to solve the problem?