No. This simply shows that you are connected (or, rather, were connected) to a web server, possibly as part of a browsing session.
The part of the left (XXX.XXX.XXX.XXX should be your IP) shows the local address of the connection. The part on the right shows the remote address. On each side, the part after the colon is the port number. On the remote side, the port is 80, the port normally used by web servers. On the left, it is a large arbitrary number. Servers tend to use low, well-known ports for incoming connections, but clients making outgoing connections do so on randomly-selected ports between 1025 and 65535.
TIME_WAIT
means that it's waiting for the remote side to terminate the connection, so all this means is that your browser was recently talking to a web server at YYY.YYY.YYY.YYY, and it the connection hasn't completely closed down yet, for various reasons.
The only reason to be concerned about this would be if you had not recently been using a web browser. Then it might indicate that something on your machine was surreptitiously contacting a webserver without your knowledge.