That's not a decision hMailserver can easily make, as hMailserver relies on the TCP/IP stack in your system for the transport. Therefor the outgoing interface is decided by the routing decision your kernel makes. Typically you will have a routing table like this:
IPv4 Route Table
===========================================================================
Active Routes:
Network Destination Netmask Gateway Interface Metric
0.0.0.0 0.0.0.0 192.168.0.42 192.168.0.16 266
127.0.0.0 255.0.0.0 On-link 127.0.0.1 306
127.0.0.1 255.255.255.255 On-link 127.0.0.1 306
127.255.255.255 255.255.255.255 On-link 127.0.0.1 306
192.168.0.0 255.255.255.0 On-link 192.168.0.16 266
192.168.0.16 255.255.255.255 On-link 192.168.0.16 266
192.168.0.255 255.255.255.255 On-link 192.168.0.16 266
224.0.0.0 240.0.0.0 On-link 127.0.0.1 306
224.0.0.0 240.0.0.0 On-link 192.168.0.16 266
255.255.255.255 255.255.255.255 On-link 127.0.0.1 306
255.255.255.255 255.255.255.255 On-link 192.168.0.16 266
===========================================================================
All traffic to the internet (0.0.0.0/0) at this system goes from Interface 192.168.0.16. Even if you add a second interface with the same gateway, netmask and metric the computer will just pick one of the two and always use that one. So there is no easy way to do what you want.