ISA 2006 can run on Windows Server 2008 32bits/64bits?
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No.
ISA uses a kernal mode driver to perform its firewall duties which is not compatible with Server 2008 (which has a very different network stack).
Forefront Threat Management Gateway (TMG) 2010 has been released, and is the new version of ISA. It is supported on 2008 x64.

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TMG2010 - http://www.microsoft.com/downloads/details.aspx?FamilyID=E05AECBC-D0EB-4E0F-A5DB-8F236995BCCD&displaylang=en – commandbreak Mar 26 '10 at 05:16
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This is going to create an interesting situation for Microsoft's support lifecycle. Windows 2003 End of Life is 14 July 2015; ISA 2006 End of Life is 10 January 2017, so you have a supported product, but no supported OS to run it on! – Richard Gadsden Oct 25 '12 at 09:05
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ISA (Internet Security and Acceleration) Server provides the two basic services of an enterprise firewall and a Web proxy ISA runs in windows Server 2006 or higher.
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1Server 2006 and higher, huh? What an awful bump to an almost 3 year old thread. – HopelessN00b Jan 21 '13 at 15:06