"How easy is it to schedule backup and other tasks? I know it's all doable, but is it more of a pain?"
Nope, pretty easy actually, you can use ExpressMaint.exe for SQL Express backups and maintenance: http://expressmaint.codeplex.com/
And as Siim K and Nick said, as far as the stress and load on SQL Express, out of those 50k hits, how many of those hits do you think are requesting data, or writing data to the DBs? If it's only a section or two of the site, I think you would be fine, but if the site is heavy on DB calls, then you are going to need to look at expanded options.