Its growing quite tall, and has some very large leaves. Def leaves of three, but I never knew poison ivy could be so large.
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I'm not certain, but as for size, there are parts of the Northeast US coast where poison ivy is everything from ground creepers to actual trees, (not ON trees. The whole small tree/large shrub is Poison Ivy) so large size does not rule it out. – Ecnerwal May 24 '23 at 18:17
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Thanks for chiming in. Didnt know they could grow into trees. Im hoping someone might be able to confirm it is or isnt poison ivy-- one way or the other. I;d hate to spray round up near my garden unless I need to. – Dave May 24 '23 at 18:58
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Assuming it is poison ivy: removal advice. DO NOT TRY TO BURN IT! That just makes poisonous caustic smoke. The best method is to rent some goats, as goats can safely eat it and then poop out perfectly fine fertilizer. The removed plant parts can lay on the ground and remain poisonous for up to three years. If you do get exposed, carefully look up treatment advice. Do not scrub with soap, this drives the poison further in your skin. – Boba Fit May 25 '23 at 00:05
2 Answers
The small leaves are poison ivy; the large leaves don't look like it but could easily be an aberrant leaf form. Obviously, if they're connected to the small leaves, then they are poison ivy. RoundUp will indeed knock it back so that it looks like it's dead, but it usually just resprouts in a month or so. You'll probably have to spray several times to actually kill it.
If you find that RoundUp doesn't ultimately work, you can use a chemical control on the cut stem, as crazy as that may sound. Because only the sap contains urushiol, the chemical that causes the reaction, it is possible after the leaves have dropped in the autumn to cut the vine with little chance of a reaction (no or little sap remains in the stem at that time). I would consider this to be a semi-safe process (i.e. wear nitrile or rubberized gloves and eye protection). After cutting the vine, brush triclopyr (AKA Stump and Brush Killer) onto the cut end of the vine and down the stem to the ground. Use alcohol wipes to clean the triclopyr container and its cap, your gloves, and your secateurs after you do this, then dispose of the wipes in the garbage, not a firepit. I'd leave the cut vine on the ground to rot. As noted elsewhere never burn poison ivy leaves or vines.

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That does indeed look like poison ivy to me, and not any of the look-alikes I know of. The leaves are larger than I've seen before too, but I've read they can be up to 7 inches long and 4 inches wide. That seems in line with what you're seeing.
Good luck and stay safe!

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All poison ivy. It will grow up trees for many feet with large leaves in moist forest conditions. – blacksmith37 May 25 '23 at 14:23