ZP4

ZP4
Identifiers
Aliases	ZP4, ZBP, ZP1, ZPB, Zp-4, zona pellucida glycoprotein 4, ZPB2, ZP1B
External IDs	OMIM: 613514 HomoloGene: 49661 GeneCards: ZP4
Gene location (Human)
Chr.	Chromosome 1 (human)
End	237,890,922 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; pancreatic ductal cell; ; tibialis anterior muscle; ; deltoid muscle; ; placenta; ; pharynx; ; thymus; ; lower lobe of lung;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	acrosin binding; identical protein binding; protein binding;
Cellular component	plasma membrane; membrane; integral component of membrane; extracellular region;
Biological process	binding of sperm to zona pellucida; negative regulation of binding of sperm to zona pellucida; positive regulation of humoral immune response; positive regulation of T cell proliferation; positive regulation of acrosome reaction; acrosomal vesicle exocytosis; single fertilization;
	Sources:Amigo / QuickGO
Orthologs
	57829
	n/a
	ENSG00000116996
	n/a
	Q12836
	n/a
	NM_021186
	n/a
	NP_067009
	n/a
	Wikidata
View/Edit Human

Zona pellucida sperm-binding protein 4, ZP-4 or avilesine, named after its discoverer Manuel Avilés Sánchez is a protein that in humans is encoded by the ZP4 gene.

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