Wilms' tumor

Wilms' tumor or Wilms tumor, also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children (rarely in adults), and occurs most commonly as a renal tumor in child patients. It is named after Max Wilms, the German surgeon (1867–1918) who first described it.

Wilms' tumor
Other namesWilms' tumor
Nephroblastoma
High magnification micrograph showing the three elements of Wilms' tumor. H&E stain.
Pronunciation
  • /vɪlmz/
SpecialtyOncology, urology, nephrology
Usual onset3–4 years old
TreatmentNephrectomy
Radiotherapy
Prognosis~90% of children are cured
Frequency~500 new diagnoses per year (United States)
Named afterMax Wilms

Approximately 650 cases are diagnosed in the U.S. annually. The majority of cases occur in children with no associated genetic syndromes; however, a minority of children with Wilms' tumor have a congenital abnormality.  It is highly responsive to treatment, with about 90 percent of children being cured.

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