Vitamin D-binding protein

GC
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1J78, 1J7E, 1KW2, 1KXP, 1LOT, 1MA9
Identifiers
Aliases	GC, DBP, DBP/GRD3, HEL-S-51, VDBG, VDBP, Gc-MAF, GcMAF, vitamin D binding protein, DBP-maf, VDB, GC vitamin D binding protein
External IDs	OMIM: 139200 MGI: 95669 HomoloGene: 486 GeneCards: GC
Gene location (Human)
Chr.	Chromosome 4 (human)
End	71,804,041 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	89,605,757 bp
RNA expression pattern
	Top expressed in
	liver; ; right lobe of liver; ; gallbladder; ; pancreatic ductal cell; ; duodenum; ; body of pancreas; ; jejunal mucosa; ; body of stomach; ; cardia; ; fundus;
	Top expressed in
	left lobe of liver; ; gallbladder; ; islet of Langerhans; ; kidney; ; sexually immature organism; ; morula; ; stomach; ; proximal tubule; ; yolk sac; ; epithelium of stomach;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	vitamin D binding; calcidiol binding; actin binding; vitamin transmembrane transporter activity;
Cellular component	blood microparticle; extracellular region; lysosomal lumen; extracellular exosome; extracellular space; cytosol;
Biological process	vitamin D metabolic process; vitamin transport; transport; vitamin transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	2638
	14473
	ENSG00000145321
	ENSMUSG00000035540
	P02774
	P21614
	NM_000583; NM_001204306; NM_001204307
	NM_008096
	NP_000574; NP_001191235; NP_001191236
	NP_032122
	Wikidata
View/Edit Human	View/Edit Mouse

Vitamin D-binding protein (DBP), also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene. DBP is genetically the oldest member of the albuminoid family and appeared early in the evolution of vertebrates.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.