C-fos-induced growth factor

VEGFD
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XV7
Identifiers
Aliases	VEGFD, VEGF-D, FIGF, C-fos induced growth factor, c-fos induced growth factor (vascular endothelial growth factor D), vascular endothelial growth factor D
External IDs	OMIM: 300091 MGI: 108037 HomoloGene: 3288 GeneCards: VEGFD
Gene location (Human)
Chr.	X chromosome (human)
End	15,384,413 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	163,185,646 bp
RNA expression pattern
	Top expressed in
	right lung; ; upper lobe of left lung; ; lactiferous duct; ; lower lobe of lung; ; gastrocnemius muscle; ; gastric mucosa; ; left ventricle; ; deltoid muscle; ; tibialis anterior muscle; ; left adrenal gland;
	Top expressed in
	left lung lobe; ; belly cord; ; right lung; ; right lung lobe; ; vas deferens; ; calvaria; ; dermis; ; uterus; ; white adipose tissue; ; endocardial cushion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; platelet-derived growth factor receptor binding; chemoattractant activity; protein binding; vascular endothelial growth factor receptor binding; growth factor activity; vascular endothelial growth factor receptor 3 binding;
Cellular component	membrane; extracellular region; platelet alpha granule lumen; extracellular space;
Biological process	dopaminergic neuron differentiation; cell differentiation; positive regulation of mast cell chemotaxis; platelet degranulation; induction of positive chemotaxis; multicellular organism development; positive regulation of cell population proliferation; cell population proliferation; positive regulation of cell division; positive chemotaxis; angiogenesis; response to hypoxia; positive regulation of endothelial cell proliferation; positive regulation of angiogenesis; vascular endothelial growth factor receptor signaling pathway; regulation of signaling receptor activity; response to bacterium; positive regulation of protein phosphorylation; sprouting angiogenesis; vascular endothelial growth factor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2277
	14205
	ENSG00000165197
	ENSMUSG00000031380
	O43915
	P97946
	NM_004469
	NM_010216; NM_001308489
	NP_004460
	NP_001295418; NP_034346
	Wikidata
View/Edit Human	View/Edit Mouse

C-fos-induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene.

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