Ursodeoxycholic acid

Ursodeoxycholic acid
Clinical data
Trade names	Actigall, Urso, others
Other names	Ursodiol
AHFS/Drugs.com	Monograph
MedlinePlus	a699047
License data	EU EMA: by INN; US DailyMed: Ursodiol;
Pregnancy; category	AU: B3;
Routes of; administration	By mouth
ATC code	A05AA02 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); CA: ℞-only; UK: POM (Prescription only); US: ℞-only; In general: ℞ (Prescription only);
Identifiers
	IUPAC name 3α,7β-dihydroxy-5β-cholan-24-oic acid; OR; (R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-; 10,13-dimethylhexadecahydro-; 1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;
CAS Number	128-13-2 ;
PubChem CID	31401;
IUPHAR/BPS	7104;
DrugBank	DB01586 ;
ChemSpider	29131 ;
UNII	724L30Y2QR;
KEGG	D00734 ;
ChEBI	CHEBI:9907 ;
ChEMBL	ChEMBL1551 ;
PDB ligand	IU5 (PDBe, RCSB PDB);
CompTox Dashboard (EPA)	DTXSID6023731 ;
ECHA InfoCard	100.004.437
Chemical and physical data
Formula	C24H40O4
Molar mass	392.580 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	203 °C (397 °F)
	SMILES O=C(O)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]4[C@H]2[C@@H](O)C[C@@H]3C[C@H](O)CC[C@@]34C)C;
	InChI InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1 ; Key:RUDATBOHQWOJDD-UZVSRGJWSA-N ;
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Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. In purified form, it has been used to treat or prevent several diseases of the liver or bile ducts.

It is available as a generic medication.

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