UGT2B7

UGT2B7
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2O6L
Identifiers
Aliases	UGT2B7, UDPGT 2B9, UDPGT2B7, UDPGTH2, UGT2B9, UDP glucuronosyltransferase family 2 member B7, UDPGT 2B7, UDPGTh-2
External IDs	OMIM: 600068 MGI: 3576103 HomoloGene: 128251 GeneCards: UGT2B7
Gene location (Human)
Chr.	Chromosome 4 (human)
End	69,112,987 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	87,240,414 bp
RNA expression pattern
	Top expressed in
	liver; ; right lobe of liver; ; kidney; ; duodenum; ; metanephric glomerulus; ; right uterine tube; ; endometrium; ; gallbladder; ; body of pancreas; ; islet of Langerhans;
	Top expressed in
	left lobe of liver; ; morula; ; duodenum; ; jejunum; ; ileum; ; Paneth cell; ; yolk sac; ; large intestine; ; colon; ; sexually immature organism;
	More reference expression data
	n/a
Gene ontology
Molecular function	glycosyltransferase activity; transferase activity; glucuronosyltransferase activity; retinoic acid binding; hexosyltransferase activity; UDP-glycosyltransferase activity;
Cellular component	integral component of membrane; organelle membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; endoplasmic reticulum;
Biological process	steroid metabolic process; metabolism; cellular glucuronidation; androgen metabolic process; lipid metabolism;
	Sources:Amigo / QuickGO
Orthologs
	7364
	231396
	ENSG00000171234
	ENSMUSG00000070704
	P16662
	n/a
	NM_001074; NM_001330719; NM_001349568
	NM_001029867
	NP_001065; NP_001317648; NP_001336497
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

UGT2B7 (UDP-Glucuronosyltransferase-2B7) is a phase II metabolism isoenzyme found to be active in the liver, kidneys, epithelial cells of the lower gastrointestinal tract and also has been reported in the brain. In humans, UDP-Glucuronosyltransferase-2B7 is encoded by the UGT2B7 gene.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.