UGT1A8

UGT1A8
Identifiers
Aliases	UGT1A8, UDPGT, UDPGT 1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H, UDP glucuronosyltransferase family 1 member A8, UGT1-01, UGT-1A, UGT1.1, UGT1A, hUG-BR1, UGT1, GNT1, UGT1A1, UDPGT 1-1
External IDs	OMIM: 606433 MGI: 3576092 HomoloGene: 133281 GeneCards: UGT1A8
Gene location (Human)
Chr.	Chromosome 2 (human)
End	233,773,300 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	88,146,719 bp
RNA expression pattern
	Top expressed in
	rectum; ; gallbladder; ; duodenum; ; urinary bladder; ; right lobe of liver; ; islet of Langerhans; ; appendix; ; renal cortex; ; thymus; ; kidney;
	Top expressed in
	hepatobiliary system; ; liver; ; duodenum; ; colon; ; renal cortex; ; proximal tubule; ; stomach; ; kidney; ; ileum; ; jejunum;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; enzyme inhibitor activity; retinoic acid binding; hexosyltransferase activity; protein homodimerization activity; glycosyltransferase activity; glucuronosyltransferase activity; fatty acid binding; steroid binding; protein heterodimerization activity; enzyme binding; UDP-glycosyltransferase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; endoplasmic reticulum;
Biological process	steroid metabolic process; coumarin metabolic process; negative regulation of steroid metabolic process; retinoic acid metabolic process; negative regulation of cellular glucuronidation; fatty acid metabolic process; cellular glucuronidation; flavonoid glucuronidation; xenobiotic glucuronidation; flavone metabolic process; metabolism; negative regulation of glucuronosyltransferase activity; negative regulation of fatty acid metabolic process; negative regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologs
	54576
	394434
	ENSG00000242366
	ENSMUSG00000090175
	Q9HAW9
	Q62452
	NM_019076
	NM_201644
	NP_061949
	NP_964006
	Wikidata
View/Edit Human	View/Edit Mouse

UDP-glucuronosyltransferase 1-8 is an enzyme that in humans is encoded by the UGT1A8 gene.

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