Trimethylsilyl chloride

Trimethylsilyl chloride, also known as chlorotrimethylsilane is an organosilicon compound (silyl halide), with the formula (CH3)3SiCl, often abbreviated Me3SiCl or TMSCl. It is a colourless volatile liquid that is stable in the absence of water. It is widely used in organic chemistry.

Trimethylsilyl chloride
Names
Preferred IUPAC name
Chlorotri(methyl)silane
Other names
Trimethylsilyl chloride
Chlorotrimethylsilane
TMSCl
Trimethylchlorosilane
TMCS
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.000.819
EC Number
  • 200-900-5
RTECS number
  • VV2710000
UNII
UN number 1298
  • InChI=1S/C3H9ClSi/c1-5(2,3)4/h1-3H3 Y
    Key: IJOOHPMOJXWVHK-UHFFFAOYSA-N Y
  • C[Si](C)(C)Cl
Properties
C3H9SiCl
Molar mass 108.64 g/mol
Appearance Colorless liquid, fumes in moist air
Density 0.856 g/cm3, liquid
Melting point −40 °C (−40 °F; 233 K)
Boiling point 57 °C (135 °F; 330 K)
Reacts
−77.36·10−6 cm3/mol
Structure
Tetrahedral at Si
Hazards
GHS labelling:
Danger
H225, H301, H312, H314, H331, H351
P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P281, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P311, P312, P321, P322, P330, P363, P370+P378, P403+P233, P403+P235, P405, P501
NFPA 704 (fire diamond)
3
3
2
Flash point −28 °C (−18 °F; 245 K)
400 °C (752 °F; 673 K)
Related compounds
Related halosilanes
Trimethylsilyl fluoride
Trimethylsilyl bromide
Trimethylsilyl iodide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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