Toxidrome

A toxidrome (a portmanteau of toxic and syndrome, coined in 1970 by Mofenson and Greensher) is a syndrome caused by a dangerous level of toxins in the body. It is often the consequence of a drug overdose. Common symptoms include dizziness, disorientation, nausea, vomiting and oscillopsia. It may indicate a medical emergency requiring treatment at a poison control center. Aside from poisoning, a systemic infection may also lead to one. Classic toxidromes are presented below, which are variable or obscured by co-ingestion of multiple drugs.

Toxidrome
SymptomsBPHRRRTempPupil sizeBowel soundsDiaphoresis
anticholinergicupupupupupdowndown
cholinergic~~~~downupup
hallucinogenicupupup~upup~
sympathomimeticupupupupupupup
sedative-hypnoticdowndowndowndown~downdown
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