Tincture of iodine

Iodine tincture
	Various bottles of tincture of iodine from the former Soviet Union
Clinical data
AHFS/Drugs.com	Monograph
Pregnancy; category	D;
Routes of; administration	Topical
ATCvet code	QD08AG (WHO) ;
Identifiers
	IUPAC name diiodane;
CAS Number	7553-56-2;
PubChem CID	807;
DrugBank	DB05382;
UNII	9679TC07X4;
Chemical and physical data
Formula	I2

Tincture of iodine, iodine tincture, or weak iodine solution is an antiseptic. It is usually 2 to 3% elemental iodine, along with potassium iodide or sodium iodide, dissolved in a mixture of ethanol and water. Tincture solutions are characterized by the presence of alcohol. It was used from 1908 in pre-operative skin preparation by Italian surgeon Antonio Grossich.

In the United Kingdom, the development of an iodine solution for skin sterilisation was pioneered by Lionel Stretton. The British Medical Journal published the detail of his work at Kidderminster Infirmary in 1909. Stretton used a much weaker solution than that used by Grossich. He claimed in 1915 that Grossich had been using a liquid akin to Liquor Iodi Fortis, and that it was he, Stretton, who had introduced the method using Tincture of Iodine BP which came to be used across the world.

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