Telomerase RNA component
Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres. TERC serves as a template for telomere replication (reverse transcription) by telomerase. Telomerase RNAs differ greatly in sequence and structure between vertebrates, ciliates and yeasts, but they share a 5' pseudoknot structure close to the template sequence. The vertebrate telomerase RNAs have a 3' H/ACA snoRNA-like domain.
| TERC | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | TERC, DKCA1, PFBMFT2, SCARNA19, TR, TRC3, hTR, Telomerase RNA component, TER | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 602322 GeneCards: TERC | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Vertebrate telomerase RNA | |
|---|---|
| Identifiers | |
| Symbol | Telomerase-vert |
| Rfam | RF00024 |
| Other data | |
| RNA type | Gene |
| Domain(s) | Eukaryote; Virus |
| PDB structures | PDBe |
| Ciliate telomerase RNA | |
|---|---|
| Identifiers | |
| Symbol | Telomerase-cil |
| Rfam | RF00025 |
| Other data | |
| RNA type | Gene |
| Domain(s) | Eukaryote |
| PDB structures | PDBe |
| Saccharomyces cerevisiae telomerase RNA | |
|---|---|
| Identifiers | |
| Symbol | Sacc_telomerase |
| Rfam | RF01050 |
| Other data | |
| RNA type | Gene |
| Domain(s) | Eukaryote |
| PDB structures | PDBe |
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