TOC1 (gene)
Timing of CAB expression 1 is a protein that in Arabidopsis thaliana is encoded by the TOC1 gene. TOC1 is also known as two-component response regulator-like APRR1.
| Timing of CAB Expression 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | APRR1 | ||||||
| Alt. symbols | TOC1, AtTOC1, MFB13.13, PSEUDO-RESPONSE REGULATOR 1 | ||||||
| Entrez | 836259 | ||||||
| RefSeq (mRNA) | NM_125531.3 | ||||||
| RefSeq (Prot) | NP_200946.1 | ||||||
| UniProt | Q9LKL2 | ||||||
| Other data | |||||||
| Chromosome | 5: 24.69 - 24.7 Mb | ||||||
| |||||||
| toc1 | |
|---|---|
| Gene | |
| Number of Exons | 6 |
| Number of Introns | 5 |
| Size | 3.49 kb |
| mRNA | |
| size | 2713 bp |
| Protein | |
| Molecular Weight | 69.2 kDa |
| pI | 7.5 |
| Amino Acids | 618 |
| Location in Arabidopsis | |
| Chromosome | 5 |
| Distance | 79.0 cM |
| Locus Tag | AT5G61380 |
TOC1 was the first plant gene that, when mutated, yielded a circadian phenotype. It codes for the transcription factor TOC1, which affects the period of plants' circadian rhythms: built-in, malleable oscillations that repeat every 24 hours. The gene codes for a transcriptional repressor, TOC1, one of five pseudo-response regulators (PRR) that mediate the period of the circadian clock in plants. The TOC1 protein is involved in the clock's evening loop, which is a repressilator that directly inhibits transcription of morning loop genes LHY and CCA1. Toc1 gene is expressed in most plant structures and cells, and has its locus on chromosome 5.