TFEB

TFEB
Identifiers
Aliases	TFEB, ALPHABHLHE35, TCFEB, transcription factor EB
External IDs	OMIM: 600744 MGI: 103270 HomoloGene: 5182 GeneCards: TFEB
Gene location (Human)
Chr.	Chromosome 6 (human)
End	41,736,259 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	48,103,344 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; blood; ; inferior olivary nucleus; ; spleen; ; inferior ganglion of vagus nerve; ; monocyte; ; parotid gland; ; anterior pituitary; ; lymph node; ; vena cava;
	Top expressed in
	esophagus; ; triceps brachii muscle; ; temporal muscle; ; vastus lateralis muscle; ; ankle; ; iris; ; ciliary body; ; gastrocnemius muscle; ; masseter muscle; ; intercostal muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein dimerization activity; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nucleus;
Biological process	autophagy; positive regulation of transcription, DNA-templated; embryonic placenta development; lysosome organization; adaptive immune response; transcription, DNA-templated; positive regulation of autophagy; positive regulation of transcription by RNA polymerase II; immune system process; humoral immune response; regulation of transcription, DNA-templated; lysosome localization;
	Sources:Amigo / QuickGO
Orthologs
	7942
	21425
	ENSG00000112561
	ENSMUSG00000023990
	P19484
	Q9R210
	NM_001167827; NM_001271943; NM_001271944; NM_001271945; NM_007162
	NM_001161722; NM_001161723; NM_011549
	NP_001161299; NP_001258872; NP_001258873; NP_001258874; NP_009093
	NP_001155194; NP_001155195; NP_035679
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor EB is a protein that in humans is encoded by the TFEB gene.

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