Sulfadimethoxine

Sulfadimethoxine
Clinical data
Trade names	Albon, Di-Methox
AHFS/Drugs.com	FDA Professional Drug Information
Routes of; administration	By mouth; can be IV in cattle
ATC code	J01ED02 (WHO) QJ01EQ09 (WHO), QP51BA01 (WHO);
Legal status
Legal status	AU: S4 (Prescription only); US: ℞-only (by veterinarian);
Pharmacokinetic data
Bioavailability	55–60%
Elimination half-life	13.1 hours in dogs
Identifiers
	IUPAC name 4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide;
CAS Number	122-11-2 ;
PubChem CID	5323;
DrugBank	DB06150 ;
ChemSpider	5132 ;
UNII	30CPC5LDEX;
KEGG	D01142 ;
ChEBI	CHEBI:32161 ;
ChEMBL	ChEMBL62193 ;
CompTox Dashboard (EPA)	DTXSID1023607 ;
ECHA InfoCard	100.004.113
Chemical and physical data
Formula	C12H14N4O4S
Molar mass	310.33 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COc1cc(nc(n1)OC)NS(=O)(=O)c2ccc(cc2)N;
	InChI InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16) ; Key:ZZORFUFYDOWNEF-UHFFFAOYSA-N ;
	(verify)

Sulfadimethoxine (or sulphadimethoxine, trade names Di-Methox or Albon) is a long-lasting sulfonamide antimicrobial medication used in veterinary medicine. It is used to treat many infections, including respiratory, urinary tract, enteric, and soft tissue infections and can be given as a standalone or combined with ormetoprim to broaden the target range. Like all sulfamides, sulfadimethoxine inhibits bacterial synthesis of folic acid by acting as a competitive inhibitor against PABA. It is the most common drug prescribed to dogs who have coccidiosis.

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