Statine

Statine is a gamma amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. It is thought to be responsible for the inhibitory activity of pepstatin because it mimics the tetrahedral transition state of peptide catalysis.

This article is about the amino acid. For the group of cholesterol lowering drugs, see Statin.
Statine
Names
IUPAC name
(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid
Identifiers
3D model (JSmol)
Abbreviations AHMHA, Sta
ChEBI
ChemSpider
ECHA InfoCard 100.161.428
UNII
  • InChI=1S/C8H17NO3/c1-5(2)3-6(9)7(10)4-8(11)12/h5-7,10H,3-4,9H2,1-2H3,(H,11,12)/t6-,7-/m0/s1
    Key: DFVFTMTWCUHJBL-BQBZGAKWSA-N
  • N[C@@H](CC(C)C)[C@@H](O)CC(O)=O
Properties
C8H17NO3
Molar mass 175.228 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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