Solvothermal synthesis

Solvothermal synthesis is a method of producing chemical compounds, in which a solvent containing reagents is put under high pressure and temperature in an autoclave. Many substances dissolve better in the same solvent in such conditions than at standard conditions, enabling reactions that would not otherwise occur and leading to new compounds or polymorphs. Solvothermal synthesis is very similar to the hydrothermal route; both are typically conducted in a stainless steel autoclave. The only difference being that the precursor solution is usually non-aqueous.

Solvothermal synthesis has been used prepare MOFs, titanium dioxide, and graphene, carbon spheres, chalcogenides and other materials.