Shikimate kinase
Shikimate kinase (EC 2.7.1.71) is an enzyme that catalyzes the ATP-dependent phosphorylation of shikimate to form shikimate 3-phosphate. This reaction is the fifth step of the shikimate pathway, which is used by plants and bacteria to synthesize the common precursor of aromatic amino acids and secondary metabolites. The systematic name of this enzyme class is ATP:shikimate 3-phosphotransferase. Other names in common use include shikimate kinase (phosphorylating), and shikimate kinase II.
| Shikimate kinase | |||||||||
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Shikimate kinase of Erwinia chrysanthemi | |||||||||
| Identifiers | |||||||||
| Symbol | SKI | ||||||||
| Pfam | PF01202 | ||||||||
| Pfam clan | CL0023 | ||||||||
| InterPro | IPR000623 | ||||||||
| PROSITE | PDOC00868 | ||||||||
| SCOP2 | 2shk / SCOPe / SUPFAM | ||||||||
| OPM superfamily | 124 | ||||||||
| OPM protein | 1e6c | ||||||||
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| shikimate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
A cartoon representation of shikimate kinase from Mycobacterium tuberculosis. α-Helices are shown in red, the central β-sheet in yellow, and loops in green | |||||||||
| Identifiers | |||||||||
| EC no. | 2.7.1.71 | ||||||||
| CAS no. | 9031-51-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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