Selamectin

Selamectin
Clinical data
Trade names	Revolution, Stronghold, Revolt
Other names	25-cyclohexyl-25-de(1-methylpropyl)-5-deoxy-22,23-dihydro-5-(hydroxyimino)-avermectin B1 monosaccharide
AHFS/Drugs.com	International Drug Names
License data	US DailyMed: Selamectin;
Routes of; administration	Topical
ATCvet code	QP54AA05 (WHO) QP53BX55 (WHO);
Legal status
Legal status	US: ℞-only;
Identifiers
CAS Number	220119-17-5 ;
PubChem CID	9578507;
ChemSpider	16738655 ;
UNII	A2669OWX9N;
ChEMBL	ChEMBL160777 ;
CompTox Dashboard (EPA)	DTXSID6045903 ;
ECHA InfoCard	100.250.168
Chemical and physical data
Formula	C43H63NO11
Molar mass	769.973 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]\5[C@@]4([C@@H](C=C(/C5=N/O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)\C)O[C@@H]1C7CCCCC7;
	InChI InChI=1S/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30,40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11,14-15,19,24,26,28-29,31-35,37-40,45,47-48H,7-9,12-13,16-18,20-23H2,1-6H3/b11-10+,25-15+,30-14+,44-36-/t24-,26-,28-,31+,32-,33-,34-,35-,37-,38-,39-,40+,42+,43+/m0/s1 ; Key:AFJYYKSVHJGXSN-XHKIUTQPSA-N ;
	(what is this?) (verify)

Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats. It is structurally related to ivermectin and milbemycin. Selamectin is not approved for human use.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.