Secosteroid

A secosteroid (/ˈsɛkoʊˌstɛrɔɪd/) is a type of steroid with a "broken" ring. The word secosteroid derives from the Latin verb secare meaning "to cut",^: 241 and 'steroid'. Secosteroids are described as a subclass of steroids under the IUPAC nomenclature.^: §3S-1 Some sources instead describe them as compounds derived from steroids.

Types or subclasses of secosteroids are defined by the carbon atoms of the parent steroid skeleton where the ring cleavage has taken place. For example, 9,10-secosteroids are derived from cleavage of the bond between carbon atoms C9 and C10 of the steroid B-ring (similarly 5,6-secosteroids, 13,14-secosteroids, etc.).^: §3S-8

The prototypical secosteroid is cholecalciferol (vitamin D₃). Its IUPAC systematic is "(5Z,7E)-(3S)-9,10-secocholestra-5,7,10(19)-trien-3-ol".^: §3S-8

Some nonsteroidal estrogens, like doisynolic acid (cleaved on the D ring) and allenolic acid, are also secosteroids or secosteroid-like compounds.

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