SRD5A3

SRD5A3
Identifiers
Aliases	SRD5A3, CDG1P, CDG1Q, KRIZI, SRD5A2L, SRD5A2L1, steroid 5 alpha-reductase 3
External IDs	OMIM: 611715 MGI: 1930252 HomoloGene: 41385 GeneCards: SRD5A3
Gene location (Human)
Chr.	Chromosome 4 (human)
End	55,373,100 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	76,303,351 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; gallbladder; ; body of pancreas; ; islet of Langerhans; ; stromal cell of endometrium; ; minor salivary gland; ; left adrenal gland; ; right adrenal gland; ; skin of abdomen; ; prefrontal cortex;
	Top expressed in
	secondary oocyte; ; internal carotid artery; ; yolk sac; ; lip; ; external carotid artery; ; condyle; ; ascending aorta; ; proximal tubule; ; sciatic nerve; ; aortic valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity, acting on the CH-CH group of donors; cholestenone 5-alpha-reductase activity; oxidoreductase activity; 3-oxo-5-alpha-steroid 4-dehydrogenase activity; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; polyprenol reductase activity;
Cellular component	cytoplasm; integral component of membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum;
Biological process	lipid metabolism; polyprenol catabolic process; androgen biosynthetic process; protein glycosylation; dolichol metabolic process; dolichyl diphosphate biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; dolichol biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	79644
	57357
	ENSG00000128039
	ENSMUSG00000029233
	Q9H8P0
	Q9WUP4
	NM_024592
	NM_020611
	NP_078868
	NP_065636
	Wikidata
View/Edit Human	View/Edit Mouse

Steroid 5-alpha-reductase 3, also known as 3-oxo-5-alpha-steroid 4-dehydrogenase 3, is an enzyme that in humans is encoded by the SRD5A3 gene. It is one of three forms of 5α-reductase.

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