SOX10

SOX10
Identifiers
Aliases	SOX10, DOM, PCWH, WS2E, WS4, WS4C, SRY-box 10, SRY-box transcription factor 10, SOX-10
External IDs	OMIM: 602229 MGI: 98358 HomoloGene: 5055 GeneCards: SOX10
Gene location (Human)
Chr.	Chromosome 22 (human)
End	37,987,422 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	79,049,440 bp
RNA expression pattern
	Top expressed in
	inferior olivary nucleus; ; sural nerve; ; inferior ganglion of vagus nerve; ; trigeminal ganglion; ; spinal ganglia; ; subthalamic nucleus; ; ventral tegmental area; ; parotid gland; ; external globus pallidus; ; superior vestibular nucleus;
	Top expressed in
	neural crest; ; external carotid artery; ; motor neuron; ; parotid gland; ; internal carotid artery; ; optic nerve; ; stria vascularis; ; sciatic nerve; ; retinal pigment epithelium; ; trigeminal ganglion;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; transcription factor binding; chromatin binding; protein binding; identical protein binding; promoter-specific chromatin binding; DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;
Cellular component	cytoplasm; nucleoplasm; nucleus; chromatin; mitochondrion; mitochondrial outer membrane; membrane; extrinsic component of mitochondrial outer membrane;
Biological process	regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; anatomical structure morphogenesis; transcription, DNA-templated; stem cell differentiation; negative regulation of transcription, DNA-templated; transcription elongation from RNA polymerase II promoter; negative regulation of Schwann cell proliferation; positive regulation of gene expression; positive regulation of myelination; cellular response to progesterone stimulus; positive regulation of transcription, DNA-templated; oligodendrocyte development; central nervous system myelination; oligodendrocyte differentiation; in utero embryonic development; neural crest cell migration; morphogenesis of an epithelium; positive regulation of neuroblast proliferation; central nervous system development; peripheral nervous system development; positive regulation of gliogenesis; cell differentiation; melanocyte differentiation; lacrimal gland development; negative regulation of apoptotic process; positive regulation of transcription by RNA polymerase II; cell maturation; enteric nervous system development; digestive tract morphogenesis; developmental growth; morphogenesis of a branching epithelium; negative regulation of canonical Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6663
	20665
	ENSG00000100146
	ENSMUSG00000033006
	P56693
	Q04888
	NM_006941
	NM_011437
	NP_008872
	NP_035567
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene.

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