4F2 cell-surface antigen heavy chain

SLC3A2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DH2, 2DH3
Identifiers
Aliases	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE, solute carrier family 3 member 2
External IDs	OMIM: 158070 MGI: 96955 HomoloGene: 1795 GeneCards: SLC3A2
Gene location (Human)
Chr.	Chromosome 11 (human)
End	62,888,880 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	8,700,733 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; stromal cell of endometrium; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; ganglionic eminence; ; upper lobe of left lung; ; skin of abdomen; ; canal of the cervix; ; minor salivary gland; ; gastric mucosa;
	Top expressed in
	submandibular gland; ; parotid gland; ; calvaria; ; spermatocyte; ; lip; ; lacrimal gland; ; iris; ; yolk sac; ; hair follicle; ; adrenal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium:sodium antiporter activity; neutral amino acid transmembrane transporter activity; catalytic activity; protein binding; double-stranded RNA binding; RNA binding; cadherin binding;
Cellular component	integral component of membrane; membrane; melanosome; plasma membrane; cell surface; apical plasma membrane; extracellular exosome; nucleus; cytosol;
Biological process	response to exogenous dsRNA; cell growth; amino acid transport; leukocyte migration; calcium ion transport; tryptophan transport; sodium ion transmembrane transport; L-alpha-amino acid transmembrane transport; transport; carbohydrate metabolic process; L-leucine import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	6520
	17254
	ENSG00000168003
	ENSMUSG00000010095
	P08195
	P10852
NM_001012661; NM_001012662; NM_001012663; NM_001012664; NM_001013251;
	NM_002394
	NM_001161413; NM_008577
	NP_001012680; NP_001012682; NP_001013269; NP_002385
	NP_001154885; NP_032603
	Wikidata
View/Edit Human	View/Edit Mouse

4F2 cell-surface antigen heavy chain is a protein that in humans is encoded by the SLC3A2 (solute carrier family 3 member 2) gene.

SLC3A2 comprises the heavy subunit of the large neutral amino acid transporter (LAT1) that is also known as CD98 (cluster of differentiation 98).

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