SIGLEC6

SIGLEC6
Identifiers
Aliases	SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1, sialic acid binding Ig like lectin 6
External IDs	OMIM: 604405 HomoloGene: 130495 GeneCards: SIGLEC6
Gene location (Human)
Chr.	Chromosome 19 (human)
End	51,531,856 bp
RNA expression pattern
	Top expressed in
	placenta; ; tibialis anterior muscle; ; rectum; ; pancreatic ductal cell; ; gallbladder; ; lymph node; ; appendix; ; smooth muscle tissue; ; upper lobe of left lung; ; gastric mucosa;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; carbohydrate binding;
Cellular component	integral component of membrane; extracellular region; plasma membrane; integral component of plasma membrane; membrane;
Biological process	cell-cell signaling; cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	946
	n/a
	ENSG00000105492
	n/a
	O43699
	n/a
NM_001177547; NM_001177548; NM_001177549; NM_001245; NM_198845;
	NM_198846
	n/a
NP_001171018; NP_001171019; NP_001171020; NP_001236; NP_942142;
	NP_942143
	n/a
	Wikidata
View/Edit Human

Sialic acid-binding Ig-like lectin 6 is a protein that in humans is encoded by the SIGLEC6 gene. The gene was originally named CD33L (CD33-like) due to similarities between these genes but later became known as OB-BP1 (OB [leptin]-binding protein 1) due to its ability to bind to this factor and, finally, SIGLEC6 as the sixth member of the SIGLEC family of receptors to be identified. The protein has also been given the CD designation CD327.

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