Renin receptor

ATP6AP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LBS, 3LC8
Identifiers
Aliases	ATP6AP2, APT6M8-9, ATP6IP2, ATP6M8-9, ELDF10, M8-9, MRXE, MRXSH, MSTP009, PRR, RENR, XMRE, XPDS, HT028, ATPase H+ transporting accessory protein 2, CDG2R
External IDs	OMIM: 300556 MGI: 1917745 HomoloGene: 38097 GeneCards: ATP6AP2
Gene location (Human)
Chr.	X chromosome (human)
End	40,606,848 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	12,483,288 bp
RNA expression pattern
	Top expressed in
	visceral pleura; ; tibia; ; germinal epithelium; ; parietal pleura; ; retinal pigment epithelium; ; orbitofrontal cortex; ; renal medulla; ; pons; ; Brodmann area 23; ; bronchial epithelial cell;
	Top expressed in
	Paneth cell; ; ciliary body; ; iris; ; retinal pigment epithelium; ; conjunctival fornix; ; substantia nigra; ; medial dorsal nucleus; ; medial geniculate nucleus; ; aortic valve; ; barrel cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; enzyme binding; signaling receptor activity;
Cellular component	integral component of membrane; plasma membrane; extracellular exosome; membrane; external side of plasma membrane; neuron projection; cell body; tertiary granule membrane; ficolin-1-rich granule membrane; extracellular space; apical plasma membrane;
Biological process	positive regulation of transforming growth factor beta1 production; rostrocaudal neural tube patterning; head morphogenesis; regulation of MAPK cascade; eye pigmentation; angiotensin maturation; positive regulation of Wnt signaling pathway; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	10159
	70495
	ENSG00000182220
	ENSMUSG00000031007
	O75787
	Q9CYN9
	NM_005765
	NM_027439
	NP_005756
	NP_081715
	Wikidata
View/Edit Human	View/Edit Mouse

The renin receptor also known as ATPase H(+)-transporting lysosomal accessory protein 2, or the prorenin receptor, is a protein that in humans is encoded by the ATP6AP2 gene.

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