RAD51

RAD51
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N0W, 1B22
Identifiers
Aliases	RAD51, BRCC5, FANCR, HHsRad51, HsT16930, MRMV2, RAD51A, RECA, RAD51 recombinase
External IDs	OMIM: 179617 MGI: 97890 HomoloGene: 2155 GeneCards: RAD51
Gene location (Human)
Chr.	Chromosome 15 (human)
End	40,732,340 bp
RNA expression pattern
	Top expressed in
	embryo; ; ganglionic eminence; ; bone marrow cells; ; secondary oocyte; ; rectum; ; spongy bone; ; stromal cell of endometrium; ; sperm; ; appendix; ; placenta;
	n/a
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; DNA binding; ATP-dependent activity, acting on DNA; DNA strand exchange activity; DNA polymerase binding; protein C-terminus binding; protein binding; four-way junction DNA binding; identical protein binding; endodeoxyribonuclease activity; ATP binding; single-stranded DNA binding; double-stranded DNA binding; single-stranded DNA helicase activity; chromatin binding; enzyme binding;
Cellular component	cytoplasm; site of double-strand break; PML body; cytoskeleton; nucleoplasm; microtubule organizing center; nuclear chromosome; mitochondrial matrix; nucleolus; mitochondrion; perinuclear region of cytoplasm; chromatin; nucleus; cytosol; protein-containing complex; condensed chromosome; condensed nuclear chromosome; lateral element; chromosome;
Biological process	strand invasion; mitotic recombination-dependent replication fork processing; reciprocal meiotic recombination; DNA recombination; regulation of double-strand break repair via homologous recombination; DNA metabolic process; positive regulation of DNA ligation; cellular response to camptothecin; double-strand break repair via homologous recombination; cellular response to ionizing radiation; mitotic recombination; protein homooligomerization; DNA repair; DNA unwinding involved in DNA replication; cellular response to DNA damage stimulus; interstrand cross-link repair; DNA recombinase assembly; negative regulation of G0 to G1 transition; telomere maintenance via recombination; telomere maintenance via telomere lengthening; replication fork processing; meiosis; chromosome organization involved in meiotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	5888
	19361
	ENSG00000051180
	n/a
	Q06609
	Q08297
	NM_001164269; NM_001164270; NM_002875; NM_133487
	NM_011234
	NP_001157741; NP_001157742; NP_002866; NP_597994
	NP_035364
	Wikidata
View/Edit Human	View/Edit Mouse

DNA repair protein RAD51 homolog 1 is a protein encoded by the gene RAD51. The enzyme encoded by this gene is a member of the RAD51 protein family which assists in repair of DNA double strand breaks. RAD51 family members are homologous to the bacterial RecA, Archaeal RadA and yeast Rad51. The protein is highly conserved in most eukaryotes, from yeast to humans.

The name RAD51 derives from RADiation sensitive protein 51.

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