RNR3
RNA, ribosomal 3, also known as RNR3, is a human gene. It is a minor isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes the rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; RNR3 has a paralog, RNR1, that arose from the whole genome duplication.
RNR3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | RNR3, RNA, ribosomal 45S cluster 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 180452 GeneCards: RNR3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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