RCC1

RCC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1A12, 1I2M, 5E1O, 5E2A, 5E1M, 5E2B, 5E1D, 5E1B
Identifiers
Aliases	RCC1, CHC1, RCC1-I, SNHG3-regulator of chromosome condensation 1
External IDs	OMIM: 179710 MGI: 1913989 HomoloGene: 55567 GeneCards: RCC1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	28,539,300 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	132,080,916 bp
RNA expression pattern
	Top expressed in
	sperm; ; islet of Langerhans; ; ganglionic eminence; ; stromal cell of endometrium; ; oocyte; ; rectum; ; lymph node; ; minor salivary gland; ; monocyte; ; secondary oocyte;
	Top expressed in
	spermatocyte; ; yolk sac; ; spermatid; ; somite; ; primitive streak; ; thymus; ; morula; ; lip; ; ankle joint; ; secondary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; guanyl-nucleotide exchange factor activity; histone binding; chromatin binding; protein binding; nucleosomal DNA binding; nucleosome binding; sulfate binding; protein heterodimerization activity;
Cellular component	cytoplasm; nuclear membrane; nucleoplasm; condensed nuclear chromosome; nucleus; chromatin; chromosome; protein-containing complex;
Biological process	chromosome segregation; G1 phase; mitotic spindle organization; cell division; spindle assembly; cell cycle; viral process; regulation of mitotic nuclear division; protein heterotetramerization; regulation of molecular function; G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	1104
	100088
	ENSG00000180198
	ENSMUSG00000028896
	P18754; Q5T081
	Q8VE37
NM_001048194; NM_001048195; NM_001048199; NM_001269; NM_001381865;
	NM_001381866
	NM_001197082; NM_133878
NP_001041659; NP_001041660; NP_001041664; NP_001260; NP_001368794;
	NP_001368795; NP_001041664.1; NP_001260.1
	NP_001184011; NP_598639
	Wikidata
View/Edit Human	View/Edit Mouse

Regulator of chromosome condensation 1, also known as RCC1, Ran guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein.

RCC1 also functions as a guanine nucleotide exchange factor for Ran GTPase.

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