RBBP4

RBBP4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XU7, 3GFC, 4PBY, 4PBZ, 4PC0, 4R7A, 5FXY
Identifiers
Aliases	RBBP4, NURF55, RBAP48, lin-53, retinoblastoma binding protein 4, RB binding protein 4, chromatin remodeling factor
External IDs	OMIM: 602923 MGI: 1194912 HomoloGene: 21153 GeneCards: RBBP4
Gene location (Human)
Chr.	Chromosome 1 (human)
End	32,686,211 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	129,229,163 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; bone marrow cells; ; monocyte; ; appendix; ; islet of Langerhans; ; stromal cell of endometrium; ; rectum; ; smooth muscle tissue; ; gallbladder; ; body of pancreas;
	Top expressed in
	Paneth cell; ; medial ganglionic eminence; ; condyle; ; fossa; ; vas deferens; ; primitive streak; ; renal corpuscle; ; abdominal wall; ; maxillary prominence; ; somite;
	More reference expression data
	n/a
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; ATP-dependent activity, acting on DNA; histone binding; histone deacetylase binding; protein binding; nucleosomal DNA binding; histone deacetylase activity;
Cellular component	NuRD complex; ESC/E(Z) complex; CAF-1 complex; Sin3 complex; nucleoplasm; NURF complex; nucleus; cytosol; protein-containing complex;
Biological process	chromatin remodeling; regulation of transcription, DNA-templated; CENP-A containing chromatin assembly; transcription, DNA-templated; regulation of cell cycle; DNA replication-dependent chromatin assembly; DNA replication; negative regulation of gene expression, epigenetic; cell cycle; negative regulation of cell population proliferation; regulation of signal transduction by p53 class mediator; histone deacetylation; response to growth hormone; negative regulation of G0 to G1 transition; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	5928
	19646
	ENSG00000162521
	ENSMUSG00000057236
	Q09028
	Q60972
	NM_005610; NM_001135255; NM_001135256
	NM_009030
	NP_001128727; NP_001128728; NP_005601
	NP_033056
	Wikidata
View/Edit Human	View/Edit Mouse

Histone-binding protein RBBP4 (also known as RbAp48, or NURF55) is a protein that in humans is encoded by the RBBP4 gene.

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