Pyrantel
Pyrantel is a medication used to treat a number of parasitic worm infections. This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. It is taken by mouth.
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| Trade names | Pin-X, Combantrin, others |
| Routes of administration | by mouth |
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| Pharmacokinetic data | |
| Bioavailability | poorly absorbed |
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| ECHA InfoCard | 100.036.143 |
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| Formula | C11H14N2S |
| Molar mass | 206.31 g·mol−1 |
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| Melting point | 178 to 179 °C (352 to 354 °F) |
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Side effects include nausea, headache, dizziness, trouble sleeping, and rash. A lower dose should be used in people with liver disease. While it does not appear to be harmful during pregnancy, it has not been studied for this use. It is unclear if it is safe for use during breastfeeding. It is in the antihelmintic family of medications. It works by paralyzing worms.
Pyrantel was initially described in 1965. It is on the World Health Organization's List of Essential Medicines. Pyrantel is available as a generic medication. It may also be used to treat worms in a number of other animals.