Pregnanolone

Pregnanolone
Names
	IUPAC name 3α-Hydroxy-5β-pregnan-20-one
	Systematic IUPAC name 1-[(1S,3aS,3bR,5aR,7R,9aS,9bS,11aS)-7-Hydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]ethan-1-one
	Other names Eltanolone; 5β-Pregnan-3α-ol-20-one; 3α,5β-Tetrahydroprogesterone; 3α,5β-THP; 3α-Hydroxy-5β-tetrahydroprogesterone
Identifiers
CAS Number	128-20-1 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:1712 ;
ChEMBL	ChEMBL210952;
ChemSpider	29132;
ECHA InfoCard	100.162.192
PubChem CID	31402;
UNII	BXO86P3XXW ;
CompTox Dashboard (EPA)	DTXSID1046342 ;
	InChI InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15-,16+,17-,18+,19+,20+,21-/m1/s1 Key: AURFZBICLPNKBZ-YZRLXODZSA-N; InChI=1/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15-,16+,17-,18+,19+,20+,21-/m1/s1 Key: AURFZBICLPNKBZ-YZRLXODZBF;
	SMILES CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C;
Properties
Chemical formula	C21H34O2
Molar mass	318.501 g·mol−1
Pharmacology
Routes of; administration	Intravenous injection
	Pharmacokinetics:
Biological half-life	0.9–3.5 hours
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Pregnanolone, also known as eltanolone, is an endogenous inhibitory neurosteroid which is produced in the body from progesterone. It is closely related to allopregnanolone, which has similar properties.

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